Description

1-(3-Chloro-4-Hexoxy-Phenyl)-2-(4,5-Dihydro-1H-Imidazol-2-Ylsulfanyl)Ethanone Hydrochloride is a specialized organic salt compound featuring a unique molecular architecture combining a chlorinated alkoxybenzene moiety with an imidazoline-thioether ketone. This compound matters as a high-value chemical intermediate and pharmacological research tool, offering precise functionality for advanced synthesis. It is primarily needed by pharmaceutical R&D teams, agrochemical developers, and manufacturers of specialty fine chemicals seeking to build complex molecular structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system or antimicrobial targets.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, or plant growth regulators due to its bioactive scaffold.
• Chemical Biology Probe: Serves as a precursor or ligand in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Material Science: Potential intermediate for creating specialized polymers or liquid crystals with unique optical or electronic properties.
• Organic Synthesis: Versatile substrate for further functionalization via its ketone, thioether, and imidazoline groups in multi-step synthetic routes.

Basic Information

Product Name	1-(3-Chloro-4-Hexoxy-Phenyl)-2-(4,5-Dihydro-1H-Imidazol-2-Ylsulfanyl)Ethanone Hydrochloride
CAS No.	160518-38-7
Molecular Formula	C17H23ClN2O2S • HCl
Molecular Weight	407.81 g/mol
Synonyms	1-(3-Chloro-4-hexoxyphenyl)-2-[(4,5-dihydro-1H-imidazol-2-yl)sulfanyl]ethanone hydrochloride; 2-[(3-Chloro-4-hexoxyphenyl)carbonylmethylthio]-2-imidazoline hydrochloride; 1-(3-Chloro-4-hexyloxyphenyl)-2-(2-imidazolin-2-ylthio)ethanone hydrochloride; Ethanone, 1-[3-chloro-4-(hexyloxy)phenyl]-2-[(4,5-dihydro-1H-imidazol-2-yl)thio]-, hydrochloride; Lofexidine Impurity; Lofexidine Related Compound; Contact for details for additional trade names.
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-4-Hexoxy-Phenyl)-2-(4,5-Dihydro-1H-Imidazol-2-Ylsulfanyl)Ethanone Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.