Description

3-Chloro-Tetrahydro-Pyran-4-One is a versatile heterocyclic building block and key chiral intermediate in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. Pharmaceutical R&D laboratories, fine chemical manufacturers, and agrochemical companies need this high-purity intermediate to facilitate efficient and scalable synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of various drug candidates, including potential antiviral and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Fine Chemical Building Block: Serves as a precursor for other functionalized tetrahydropyran derivatives and complex heterocycles in specialty chemistry.
• Academic & Industrial Research: Employed in methodological development and exploration of new chemical spaces in medicinal and synthetic chemistry.
• Ligand and Catalyst Development: Acts as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Chloro-Tetrahydro-Pyran-4-One
CAS No.	160427-98-5
Molecular Formula	C5H7ClO2
Molecular Weight	134.56 g/mol
Synonyms	3-Chloro-4-oxotetrahydropyran; 3-Chloro-4-oxooxane; 3-Chlorotetrahydropyran-4-one; 4-Oxo-3-chlorotetrahydropyran; Tetrahydro-3-chloro-4H-pyran-4-one; 3-Chloro-4-oxotetrahydro-2H-pyran; 3-Chloro-4-oxotetrahydro-2H-pyran-4-one; 3-Chloro-4-oxotetrahydropyran-4-one
EINECS	Contact for details

Quality Control

Our 3-Chloro-Tetrahydro-Pyran-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.