Description

(2R,3R,4R)-1,2,3,4-Octadecanetetrol 2-Methanesulfonate is a high-purity, stereochemically defined chemical intermediate of significant interest in advanced organic synthesis. Its precise stereochemistry and functional groups make it a valuable building block for the development of complex, biologically active molecules. This compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex lipid-based or carbohydrate-mimetic drugs.
• Medicinal Chemistry Research: Used as a building block for constructing molecular libraries to explore structure-activity relationships (SAR) in drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Employed in the custom synthesis of specialty chemicals, complex natural product analogs, and advanced materials requiring specific stereochemical control.
• Biochemical Research: Potential use as a precursor or analog in studies involving cell membrane components, signaling lipids, or enzyme substrates.

Basic Information

Product Name	(2R,3R,4R)-1,2,3,4-Octadecanetetrol 2-Methanesulfonate
CAS No.	160280-65-9
Molecular Formula	C19H40O7S
Molecular Weight	412.58 g/mol
Synonyms	1,2,3,4-Octadecanetetrol, 2-(methylsulfonate), (2R,3R,4R)-; D-erythro-Octadecasphinganine 2-Methanesulfonate; (2R,3R,4R)-2-(Methylsulfonyloxy)octadecane-1,3,4-triol; Sphinganine Methanesulfonate Derivative; C18-Sphinganine 2-O-Methanesulfonate; Octadecanetetrol Methanesulfonate Ester; (2R,3R,4R)-1,2,3,4-Tetrahydroxyoctadecane 2-Methanesulfonate
EINECS	Contact for details

Quality Control

Every batch of (2R,3R,4R)-1,2,3,4-Octadecanetetrol 2-Methanesulfonate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as chiral purity, chemical purity (HPLC), and residual solvents. Our quality system supports compliance with cGMP standards for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.