Description

(S)-Tetrahydro-2H-pyran-2-carboxylic acid methyl ester (CAS 159572-48-2) is a high-value chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functionalized pyran ring structure make it a critical precursor for the development of complex, biologically active molecules. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and infectious diseases.
• Asymmetric Catalysis: Used as a starting material or ligand precursor in the development of novel chiral catalysts for enantioselective transformations.
• Agrochemical Synthesis: Employed in the research and production of advanced pesticides and herbicides where stereochemistry influences biological activity.
• Flavor & Fragrance Chemistry: Acts as a building block for the synthesis of complex, naturally occurring odorants and flavor compounds with specific stereochemical profiles.
• Material Science Research: Investigated as a monomer or modifying agent for the creation of novel polymers with specific architectural or functional properties.
• Academic & Process R&D: Utilized in university and industrial laboratories for methodological development and scale-up studies of stereocontrolled synthetic routes.

Basic Information

Product Name	(S)-Tetrahydro-2H-pyran-2-carboxylic acid methyl ester
CAS No.	159572-48-2
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(S)-Methyl tetrahydro-2H-pyran-2-carboxylate; (S)-Methyl oxane-2-carboxylate; Methyl (S)-tetrahydro-2H-pyran-2-carboxylate; (S)-2-Methoxycarbonyltetrahydropyran; (S)-Tetrahydro-2-pyrancarboxylic acid methyl ester; 2H-Pyran-2-carboxylic acid, tetrahydro-, methyl ester, (S)- (9CI); (S)-Methyl 2-oxanecarboxylate
EINECS	Contact for details

Quality Control

Our production of (S)-Tetrahydro-2H-pyran-2-carboxylate methyl ester adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high enantiomeric purity and chemical identity, with critical parameters verified by chiral HPLC, NMR, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and enantiomeric purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.