Description

2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Trichloroacetimidate is a high-purity, advanced glycosyl donor used in stereoselective glycosylation reactions. This compound is critical for the efficient and controlled synthesis of complex oligosaccharides and glycoconjugates. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and carbohydrate chemistry sectors, enabling the development of novel therapeutics, vaccines, and diagnostic agents.

Application

• Glycosylation Reagent: A key donor for the stereoselective synthesis of α-mannosidic linkages in oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) for antiviral, anticancer, and anti-inflammatory drugs.
• Carbohydrate Chemistry Research: An indispensable tool for academic and industrial research into carbohydrate structure, function, and synthesis.
• Glycobiology Studies: Enables the construction of defined glycan structures for studying protein-carbohydrate interactions and biological signaling pathways.
• Vaccine Development: Used in the synthesis of carbohydrate-based antigens for conjugate vaccine candidates.
• Diagnostic Reagent Synthesis: Serves as a precursor for labeled glycans used in diagnostic assays and imaging probes.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Trichloroacetimidate
CAS No.	158250-57-8
Molecular Formula	C16H20Cl3NO10
Molecular Weight	492.69 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl trichloroacetimidate; α-D-Mannopyranosyl trichloroacetimidate, 2,3,4,6-tetraacetate; Trichloroacetimidic acid 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl ester; Mannosyl Trichloroacetimidate Donor; Tetraacetyl Mannosyl Trichloroacetimidate; α-Mannosyl Donor; Glycosyl Donor 158250-57-8
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Mannopyranosyl Trichloroacetimidate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.