Description

Cyclohexanecarboxylic Acid, 3-Amino-2-Hydroxy-, (1S,2S,3S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its multifunctional structure, incorporating carboxylic acid, amino, and hydroxyl groups on a rigid cyclohexane scaffold, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs), chiral catalysts, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including antibiotics and central nervous system (CNS) drugs.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Peptidomimetic & Constrained Amino Acid Analogue: Serves as a backbone for designing conformationally restricted peptides to improve metabolic stability and bioavailability.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and natural product derivatives.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3-Amino-2-Hydroxy-, (1S,2S,3S)- (9Ci)
CAS No.	158195-48-3
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(1S,2S,3S)-3-Amino-2-hydroxycyclohexanecarboxylic acid; (1S,2S,3S)-3-Amino-2-hydroxycyclohexane-1-carboxylic acid; cis-3-Amino-2-hydroxycyclohexanecarboxylic acid (specifying (1S,2S,3S) stereochemistry); 3-Amino-2-hydroxycyclohexanecarboxylic acid (1S,2S,3S)-isomer; AHCCH; Chiral cyclohexane amino acid derivative
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 3-Amino-2-Hydroxy-, (1S,2S,3S)- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot undergoes rigorous analytical testing, including chiral purity verification by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.