Description

Calix[4]-Bis-Crown-6 is a sophisticated macrocyclic compound belonging to the calixarene family, functionalized with two crown-ether-like polyether bridges. This molecular architecture is engineered for its exceptional selectivity in binding specific cations, particularly alkali and alkaline earth metals, making it a critical component in advanced separation and sensing technologies. It is essential for researchers and manufacturers in the fields of ion-selective extraction, chemical sensors, and supramolecular chemistry.

Application

• Ion-Selective Electrodes (ISEs) and Sensors: Acts as a highly selective ionophore for potentiometric detection of target ions like cesium or potassium.
• Liquid-Liquid Extraction Processes: Used in the selective separation and recovery of valuable or radioactive metal ions from complex mixtures.
• Supramolecular Assembly & Host-Guest Chemistry: Serves as a versatile building block for constructing functional molecular devices and capsules.
• Membrane Technology: Incorporated into polymer membranes to create selective barriers for ion transport in separation and purification systems.
• Catalysis: Can be used to design catalyst systems where the cavity and binding sites control substrate orientation and reaction environment.
• Analytical Chemistry Reagents: Employed as a complexing agent in chromatographic methods or spectroscopic analysis for metal ion determination.

Basic Information

Item	Detail
Product Name	Calix[4]-Bis-Crown-6
CAS No.	157769-14-7
Molecular Formula	C44H48O12
Molecular Weight	744.85 g/mol
Synonyms	1,3-Alternate-25,27-Bis(crown-6)-26,28-dihydroxycalix[4]arene; Calix[4]arene-bis-crown-6; 25,27-Bis[(ethoxycarbonyl)methoxy]-26,28-dihydroxycalix[4]arene-crown-6; p-tert-Butylcalix[4]arene-bis-crown-6; BC6; Cs-Selective Calixarene Crown Ether; Ionophore VI
EINECS	Contact for details

Quality Control

Our Calix[4]-Bis-Crown-6 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, NMR for structural confirmation, and elemental analysis. A Certificate of Analysis (COA) detailing the specific results for purity, identity, and other critical parameters is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.