Description

2H-Pyran-2-Ol,Tetrahydro-3,5-Dimethyl-6-(1-Methylethyl)-,[2R-(2Alpha,3Bta,5Alpha,6Alpha)]-(9Ci) CAS NO 157640-53-4 is a high-purity, stereochemically defined cyclic ether alcohol, valued for its role as a versatile chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry is critical for imparting specific biological activity and physical properties in final products. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create enantiomerically pure target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Fine Chemical Manufacturing: Serves as a precursor for fragrances, flavors, and other specialty chemicals requiring high stereochemical purity.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts and synthetic methodologies.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique optical or mechanical properties.

Basic Information

Product Name	2H-Pyran-2-Ol,Tetrahydro-3,5-Dimethyl-6-(1-Methylethyl)-,[2R-(2Alpha,3Bta,5Alpha,6Alpha)]-(9Ci)
CAS No.	157640-53-4
Molecular Formula	C10H20O2
Molecular Weight	172.26 g/mol
Synonyms	(2R,3S,5R,6R)-3,5-Dimethyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-ol; (2R,3S,5R,6R)-3,5-Dimethyl-6-isopropyltetrahydro-2H-pyran-2-ol; 6-Isopropyl-3,5-dimethyltetrahydro-2H-pyran-2-ol (stereoisomer); Tetrahydro-3,5-dimethyl-6-(1-methylethyl)-2H-pyran-2-ol, [2R-(2α,3β,5α,6α)]-; Stereoisomer of Dihydromintlactone; Chiral Pyranol Intermediate
EINECS	Contact for details

Quality Control

Every batch of this chiral intermediate is produced under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles, typically determined by advanced chromatographic methods (HPLC, GC). Our quality commitment ensures the material meets the stringent requirements for GMP-grade pharmaceutical development and high-end research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.