Description

Cyclopropanecarboxaldehyde, 2-(Trimethylsilyl)-, trans- (9Ci) is a specialized organosilicon building block featuring a reactive aldehyde group adjacent to a cyclopropane ring. This compound matters for its unique structural motif, which is highly valuable in advanced organic synthesis for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly those requiring cyclopropane or silicon-containing pharmacophores.
• Asymmetric Synthesis: Used as a substrate or precursor in stereoselective reactions, including aldol condensations and nucleophilic additions, to create enantiomerically pure compounds.
• Agrochemical Research: Employed in the development of new pesticides and herbicides where the cyclopropane moiety can enhance biological activity.
• Material Science Precursor: Acts as a starting material for synthesizing functionalized silanes or silicon-based polymers with specific optical or electronic properties.
• Cross-Coupling Reactions: The aldehyde group and potential leaving groups on the silicon make it suitable for use in various metal-catalyzed coupling reactions.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, exploring new reaction pathways involving strained rings and silicon chemistry.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 2-(Trimethylsilyl)-, trans- (9Ci)
CAS No.	157556-35-9
Molecular Formula	C7H14OSi
Molecular Weight	142.27 g/mol
Synonyms	trans-2-(Trimethylsilyl)cyclopropanecarboxaldehyde; (1R,2S)-rel-2-(Trimethylsilyl)cyclopropanecarboxaldehyde; 2-(Trimethylsilyl)cyclopropanecarbaldehyde; Cyclopropanecarboxaldehyde, 2-(trimethylsilyl)-, (1R,2S)-rel-; trans-2-Trimethylsilylcyclopropanecarbaldehyde; (1R,2S)-2-(Trimethylsilyl)cyclopropanecarboxaldehyde; 2-TMS-cyclopropanecarbaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 2-(Trimethylsilyl)-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.