Description

Cyclopropanecarboxaldehyde, 2-(Trimethylsilyl)-, cis- (9Ci) is a specialized organosilicon building block featuring a reactive aldehyde group adjacent to a cyclopropane ring. This compound is highly valued in advanced organic synthesis for its ability to introduce both the strained cyclopropane moiety and a protected silyl group, enabling complex molecular construction. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for constructing complex drug candidates, particularly those requiring cyclopropane rings for conformational restriction or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane structure can confer unique biological activity.
• Material Science Research: Serves as a precursor for synthesizing functionalized silanes and silicon-containing polymers with tailored properties.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in the development of new catalytic systems due to its stereodefined structure.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and C-C bond formation strategies.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 2-(Trimethylsilyl)-, cis- (9Ci)
CAS No.	157556-34-8
Molecular Formula	C7H14OSi
Molecular Weight	142.27 g/mol
Synonyms	cis-2-(Trimethylsilyl)cyclopropanecarboxaldehyde; (1S,2S)-2-(Trimethylsilyl)cyclopropanecarbaldehyde; 2-(Trimethylsilyl)cyclopropanecarbaldehyde, cis-; (1R,2R)-2-(Trimethylsilyl)cyclopropanecarbaldehyde; Cyclopropanecarboxaldehyde, 2-(trimethylsilyl)-, (1S,2S)-rel-; TMS-cyclopropanecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxaldehyde, 2-(Trimethylsilyl)-, cis- (9Ci) is produced and analyzed under strict quality protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This material is easily oxidized and light-sensitive. Keep container tightly sealed in a cool, dry, and well-ventilated place. Separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.