Description

n-Methylindole-2-Tributylstannane is a specialized organotin reagent featuring a functionalized indole core, widely utilized in advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a key building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic structures. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• As a crucial coupling partner in Stille cross-coupling reactions for C-C bond formation.
• Synthesis of complex indole derivatives with potential biological activity for pharmaceutical R&D.
• Building block for advanced material precursors, including organic semiconductors and ligands for catalysis.
• Intermediate in the development of agrochemicals and specialty fine chemicals.
• Used in methodology development and scale-up processes within process chemistry.
• Facilitates the introduction of the n-methylindole moiety into target molecules under mild conditions.

Basic Information

Product Name	n-Methylindole-2-Tributylstannane
CAS No.	157427-46-8
Molecular Formula	C21H35NSn
Molecular Weight	420.21 g/mol
Synonyms	1-Methyl-2-(tributylstannyl)-1H-indole; 2-Tributylstannyl-1-methylindole; Tributyl(1-methyl-1H-indol-2-yl)stannane; 1-Methyl-2-tributylstannylindole; N-Methyl-2-tributylstannylindole; Stannane, tributyl(1-methyl-1H-indol-2-yl)-; (1-Methyl-1H-indol-2-yl)tributylstannane
EINECS	Contact for details

Quality Control

Our n-Methylindole-2-Tributylstannane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹⁹Sn) and HPLC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to maximize shelf-life stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	28.0 - 29.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.