Description

2-Bromo-3-Pyridyl Trifluoromethanesulfonate is a high-value triflate ester building block, specifically functionalized on the pyridine ring. This compound is essential for facilitating challenging cross-coupling reactions, enabling the efficient synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials chemists for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity for structure-activity relationship (SAR) studies.
• Cross-Coupling Reactions: Serves as an excellent electrophile in palladium-catalyzed reactions such as Suzuki, Negishi, and Stille couplings to introduce the 2-bromo-3-pyridyl moiety.
• Ligand and Material Science: Employed in the creation of specialized ligands for catalysis and as a building block for organic electronic materials.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry in both academic and industrial R&D laboratories.

Basic Information

Product Name	2-Bromo-3-Pyridyl Trifluoromethanesulfonate
CAS No.	157373-97-2
Molecular Formula	C7H3BrF3NO3S
Molecular Weight	317.07 g/mol
Synonyms	2-Bromo-3-pyridyl triflate; 2-Bromo-3-pyridinyl trifluoromethanesulfonate; 3-Bromo-2-pyridyl trifluoromethanesulfonate; Trifluoromethanesulfonic acid 2-bromo-3-pyridyl ester; 2-Bromo-3-trifluoromethanesulfonyloxypyridine; (2-Bromopyridin-3-yl) trifluoromethanesulfonate; 157373-97-2
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Pyridyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.