Description

5-Bromo-2,3-Diaminobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring both bromine and amine functional groups on a trifluoromethyl-substituted benzene ring. This unique structure makes it a critical building block for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, dyes, and pigments with unique optical or electronic properties.
• Ligand and Catalyst Development: The diamine functionality allows for the creation of complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: Essential for medicinal chemistry and drug discovery programs focused on building fluorinated compound libraries to explore structure-activity relationships (SAR).

Basic Information

Product Name	5-Bromo-2,3-Diaminobenzotrifluoride
CAS No.	157026-19-2
Molecular Formula	C7H5BrF3N2
Molecular Weight	255.03 g/mol
Synonyms	2,3-Diamino-5-bromobenzotrifluoride; 5-Bromo-2,3-diamino-α,α,α-trifluorotoluene; 1-Bromo-2,3-diamino-5-(trifluoromethyl)benzene; 5-Bromo-2,3-diamino-α,α,α-trifluorotoluene; 2,3-Diamino-5-bromo-α,α,α-trifluorotoluene; Benzenamine, 5-bromo-2,3-diamino-α,α,α-trifluoro-; 157026-19-2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Diaminobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to supply chain integrity and regulatory compliance (including REACH) ensures reliable material for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.