Description

5-(Tributylstannyl)Thiazole CAS NO 157025-33-7 is a specialized organotin compound featuring a thiazole heterocycle, serving as a versatile building block in advanced synthetic chemistry. Its core value lies in its ability to act as a stannylating agent, facilitating efficient carbon-carbon and carbon-heteroatom bond formation through cross-coupling reactions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those containing thiazole moieties with potential biological activity.
• Agrochemical Synthesis: Used in constructing novel fungicides, herbicides, and insecticides that leverage the thiazole ring system.
• Material Science Research: Building block for creating organic semiconductors, ligands for catalysis, and other functional organic materials.
• Cross-Coupling Reactions: Acts as a stamane reagent in Stille coupling reactions to form biaryl and heteroaryl compounds.
• Chemical Synthesis: Versatile reagent for introducing the 5-thiazolyl group into complex molecular architectures under mild conditions.
• Laboratory Scale & Process Development: Suitable for R&D and scale-up activities requiring high-purity, consistent organometallic reagents.

Basic Information

Product Name	5-(Tributylstannyl)Thiazole
CAS No.	157025-33-7
Molecular Formula	C15H27NSSn
Molecular Weight	372.13 g/mol
Synonyms	5-(Tributylstannyl)-1,3-thiazole; Tributyl(5-thiazolyl)stannane; 5-Thiazolyltributyltin; Stannane, tributyl(5-thiazolyl)-; 5-(Tributyltin)thiazole; Thiazole, 5-(tributylstannyl)-; 5-Tributylstannylthiazole; Tributyl(2-thiazolyl)stannane (alternative numbering)
EINECS	Contact for details

Quality Control

Our 5-(Tributylstannyl)Thiazole is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 119Sn) and HPLC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity organometallic intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C under an inert atmosphere (argon or nitrogen) to maximize shelf-life stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR Purity	≥ 95.0%
Tin (Sn) Content	31.0 - 33.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.