Description

(3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Ol is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its complex fused bicyclic furan structure, which serves as a critical scaffold in the synthesis of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel therapeutics, including antiviral and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules and proprietary APIs.
• Antiviral Drug Research: Used as a core structural unit in the development of nucleoside analogues and other antiviral compounds.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce stereochemical complexity.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing diverse compound libraries in drug discovery and lead optimization programs.
• Process Chemistry: Utilized in the scale-up and route development for the commercial manufacturing of target molecules.
• Fine Chemical Production: Acts as a precursor for other high-value, specialized chemicals and reagents.

Basic Information

Product Name	(3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Ol
CAS No.	156928-09-5
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol; (3R,3aS,6aR)-Tetrahydro-3H-furo[2,3-b]furan-3-ol; L-Fucose derivative; Bicyclic furan alcohol; (3R,3aS,6aR)-Perhydrofuro[2,3-b]furan-3-ol; 3(R)-Hydroxyhexahydrofuro[2,3-b]furan; (3R,3aS,6aR)-3-Hydroxyhexahydro-2H-furo[2,3-b]furan
EINECS	Contact for details

Quality Control

Our (3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.