Description

Ethanone, 1-[(1R,2R)-2-(Hydroxymethyl)Cyclopropyl]-, Rel- (9Ci) is a high-purity, chiral cyclopropane derivative that serves as a critical advanced intermediate in modern organic synthesis. This compound is valued for its unique stereochemistry and functional groups, enabling the construction of complex molecular architectures with precise spatial control. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic compounds, particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its cyclopropane moiety can contribute to biological activity and stability.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Serves as a specialized intermediate for the manufacture of complex flavors, fragrances, and other high-value specialty chemicals.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	Ethanone, 1-[(1R,2R)-2-(Hydroxymethyl)Cyclopropyl]-, Rel- (9Ci)
CAS No.	156742-99-3
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	rel-(1R,2R)-2-(Hydroxymethyl)cyclopropyl methyl ketone; 1-[(1R,2R)-2-(Hydroxymethyl)cyclopropyl]ethanone; (1R,2R)-2-(Acetylmethyl)cyclopropanemethanol; Chiral Cyclopropyl Hydroxymethyl Ketone; (1R,2R)-2-(1-Oxoethyl)cyclopropanemethanol
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1R,2R)-2-(Hydroxymethyl)Cyclopropyl]-, Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR to confirm identity, assay, enantiomeric excess, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.