Description

8-Bromo-1,2,3,4-Tetrahydronaphthalen-2-Amine is a versatile brominated tetralin amine derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a primary amine group on a partially saturated naphthalene scaffold, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex amine functionalities.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new reaction pathways in university and corporate research laboratories.
• Ligand Synthesis: Used to prepare novel chiral or achiral ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	8-Bromo-1,2,3,4-Tetrahydronaphthalen-2-Amine
CAS No.	156605-51-5
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	8-Bromo-2-amino-1,2,3,4-tetrahydronaphthalene; 2-Amino-8-bromo-1,2,3,4-tetrahydronaphthalene; 8-Bromo-2-tetralinamine; 1,2,3,4-Tetrahydronaphthalen-2-amine, 8-bromo-; 8-Bromo-1,2,3,4-tetrahydro-2-naphthylamine; 8-Bromo-2-aminotetralin; 8-Bromo-2-ATN
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,2,3,4-Tetrahydronaphthalen-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.