Description

Tetrahydrofuran-3-Yl Methanesulfonate is a versatile and reactive chemical building block, specifically a mesylate ester derivative of a tetrahydrofuran scaffold. This compound is of significant value in advanced organic synthesis and pharmaceutical research, where it serves as a key intermediate for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as nucleoside synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside analogs and other bioactive molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive mesylate group.
• Organic Synthesis: Serves as a versatile electrophile in alkylation reactions and for introducing the tetrahydrofuran-3-yl moiety into target compounds.
• Process Chemistry: Employed in route scouting and scale-up for the production of complex fine chemicals.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced materials.

Basic Information

Product Name	Tetrahydrofuran-3-Yl Methanesulfonate
CAS No.	156380-34-6
Molecular Formula	C6H12O4S
Molecular Weight	180.22 g/mol
Synonyms	3-Tetrahydrofuranyl methanesulfonate; Tetrahydro-3-furanyl methanesulfonate; 3-(Methanesulfonyloxy)tetrahydrofuran; THF-3-yl mesylate; 3-Hydroxytetrahydrofuran methanesulfonate ester; Mesylic acid tetrahydrofuran-3-yl ester; (Tetrahydrofuran-3-yl) methylsulfonate
EINECS	Contact for details

Quality Control

Our Tetrahydrofuran-3-Yl Methanesulfonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.