Description

n-(4-Acetylphenyl)-2-Chloropropanamide is a specialized organic intermediate featuring both acetyl and chloropropanamide functional groups on a phenyl ring. This unique molecular architecture makes it a valuable building block for synthesizing more complex chemical entities, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in fine chemical synthesis, where precise molecular control is critical for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides or plant growth regulators, leveraging its halogenated structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers or organic electronic materials due to its aromatic and amide functionalities.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring high-purity intermediates.

Basic Information

Product Name	n-(4-Acetylphenyl)-2-Chloropropanamide
CAS No.	156369-45-8
Molecular Formula	C11H12ClNO2
Molecular Weight	225.67 g/mol
Synonyms	2-Chloro-N-(4-acetylphenyl)propanamide; 1-(4-((2-Chloropropanoyl)amino)phenyl)ethan-1-one; N-(4-Acetylphenyl)-2-chloropropionamide; p-Acetamidophenyl 2-chloropropionate (incorrect but common misnomer); 4-Acetyl-2-chloropropionanilide; 156369-45-8; Propanamide, N-(4-acetylphenyl)-2-chloro-
EINECS	Contact for details

Quality Control

Our n-(4-Acetylphenyl)-2-Chloropropanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. As with all fine chemicals, proper handling procedures should be followed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.