Description

Cyclopentanecarboxylic Acid, 2-Amino-3-Methylene-, cis- (9Ci) is a specialized chiral building block featuring a cyclopentane ring system with both amino and carboxylic acid functional groups. This unique structure makes it a valuable intermediate for the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for creating novel drug candidates, such as protease inhibitors or other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in classes like protease inhibitors.
• Peptidomimetics Synthesis: Used to construct constrained peptide analogs and peptidomimetics due to its rigid cyclopentane backbone and functional handles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and catalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the discovery and development of new, more selective pesticides and herbicides.
• Material Science: Potential monomer or additive for creating specialized polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Amino-3-Methylene-, cis- (9Ci)
CAS No.	156292-95-4
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	cis-2-Amino-3-methylenec cyclopentanecarboxylic Acid; (1S,2R)-2-Amino-3-methylidenecyclopentane-1-carboxylic acid; 2-Amino-3-methylenec cyclopentanecarboxylic acid, cis-; 2-Aza-3-methylenebicyclo[3.3.0]octane-1-carboxylic acid derivative; Aminomethylene cyclopentanecarboxylic acid; CAS 156292-95-4
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Amino-3-Methylene-, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.