Description

3-Bromo-5-(tert-Butyl)Aniline is a high-purity, halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a bulky tert-butyl group, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the bromine atom and aniline core enable specific biological activity.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, dyes, and pigments.
• Ligand and Catalyst Development: The aniline nitrogen and aromatic bromine provide handles for creating complex ligands used in catalytic systems for fine chemical manufacturing.
• Academic and Industrial R&D: A valuable reagent for methodological studies in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and other transformative organic reactions.

Basic Information

Product Name	3-Bromo-5-(tert-Butyl)Aniline
CAS No.	156264-80-1
Molecular Formula	C10H14BrN
Molecular Weight	228.13 g/mol
Synonyms	3-Bromo-5-tert-butylaniline; 5-tert-Butyl-3-bromoaniline; 1-Amino-3-bromo-5-tert-butylbenzene; 3-Bromo-5-(1,1-dimethylethyl)benzenamine; Benzenamine, 3-bromo-5-(1,1-dimethylethyl)-; 3-Bromo-5-(tert-butyl)phenylamine; 3-Bromo-5-tert-butylbenzenamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(tert-Butyl)Aniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 70 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.