Description

1,6,7,8-Indolizinetetrol, Octahydro-, Tetraacetate (Ester), 1S-(1.Alpha.,6.Alpha.,7.Beta.,8.Beta.,8A.Beta.)- is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its complex, functionalized indolizine scaffold, which serves as a versatile building block for the development of novel pharmacologically active compounds. This product is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in classes targeting neurological or metabolic diseases.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Natural Product Synthesis: Employed in the total or semi-synthesis of complex alkaloids and other natural products containing the indolizidine or related heterocyclic cores.
• Academic Research: Utilized in universities and research institutes for studies in asymmetric synthesis, methodology development, and chemical biology.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1,6,7,8-Indolizinetetrol, Octahydro-, Tetraacetate (Ester), 1S-(1.Alpha.,6.Alpha.,7.Beta.,8.Beta.,8A.Beta.)-
CAS No.	156257-97-5
Molecular Formula	C18H26O8
Molecular Weight	370.40 g/mol
Synonyms	(1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol Tetraacetate; (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrakis(acetyloxy)octahydroindolizine; 1S-(1α,6α,7β,8β,8aβ)-Octahydro-1,6,7,8-indolizinetetrol Tetraacetate; SW 163B; SW-163B; Tetra-O-acetyl-1,6,7,8-tetrahydroxyindolizidine; Indolizidine Tetraacetate Derivative
EINECS	Contact for details

Quality Control

Our 1,6,7,8-Indolizinetetrol, Octahydro-, Tetraacetate (Ester) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.