Description

2-Amino-4-(3-Chlorophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-value chromene derivative, a key heterocyclic building block prized for its complex molecular architecture. This compound is essential for research and development in advanced organic synthesis, particularly in the creation of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of new therapeutic agents and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Organic Synthesis Building Block: Used in the construction of complex polycyclic frameworks and heterocyclic compounds due to its reactive amino, cyano, and carbonyl functional groups.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to identify new bioactive molecules.
• Agrochemical Development: Investigated as an intermediate for creating new crop protection agents and pesticides with novel modes of action.
• Material Science Research: Potential precursor for the development of organic electronic materials or specialty dyes and pigments.

Basic Information

Product Name	2-Amino-4-(3-Chlorophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	156176-91-9
Molecular Formula	C16H13ClN2O2
Molecular Weight	300.74 g/mol
Synonyms	2-Amino-4-(3-chlorophenyl)-5-oxo-4H,5H,6H,7H,8H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-(3-chlorophenyl)-5,6,7,8-tetrahydro-5-oxo-; 2-Amino-4-(3-chlorophenyl)-5-oxo-4,5,6,7,8,9-hexahydro-1-benzopyran-3-carbonitrile; 3-Chloro-2'-amino-4'H-spiro[chromene-3,1'-cyclohexan]-4-one-2-carbonitrile (related structural name); Chromene-3-carbonitrile derivative (common class name).
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-(3-Chlorophenyl)-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.