Description

Methanesulfonic Acid, Trifluoro-, 1,6,8-Tris(Acetyloxy)Octahydro-7-Indolizinyl Ester, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of sophisticated pharmaceutical molecules and fine chemicals, where its unique stereochemistry and functional groups enable precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those with indolizidine or related alkaloid-like structures.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its trifluoromethanesulfonate ester group for introducing specific biological activity.
• Asymmetric Synthesis: Serves as a chiral building block or auxiliary in stereoselective synthesis due to its defined stereocenters (1S configuration).
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including dyes, flavors, and fragrances requiring complex ester functionalities.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, especially in studies involving esterification, fluorination, and heterocyclic chemistry.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced polymeric or coordination complex materials.

Basic Information

Item	Detail
Product Name	Methanesulfonic Acid, Trifluoro-, 1,6,8-Tris(Acetyloxy)Octahydro-7-Indolizinyl Ester, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156150-93-5
Molecular Formula	C17H22F3NO8S
Molecular Weight	457.42 g/mol
Synonyms	1S-(1α,6β,7α,8β,8aβ)-1,6,8-Tris(acetyloxy)octahydro-7-indolizinyl trifluoromethanesulfonate; (1S,6R,7S,8R,8aR)-1,6,8-Triacetoxyindolizidin-7-yl triflate; Trifluoromethanesulfonic acid 1,6,8-triacetoxyindolizidin-7-yl ester; 7-Triflyloxy-1,6,8-triacetoxyindolizidine; Indolizidine-7-yl triflate triacetate; 156150-93-5; 7-O-Triflyl-1,6,8-tri-O-acetylindolizidine
EINECS	Contact for details

Quality Control

Our high-purity synthetic intermediate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent derivative, it should be stored separately from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.