Description

Methanesulfonic Acid, Trifluoro-, 2-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Ethyl Ester is a specialized, high-purity chemical building block designed for advanced synthetic applications. This compound is valued for its unique trifluoromethanesulfonate (triflate) ester group, which serves as an excellent leaving group in cross-coupling and nucleophilic substitution reactions. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functional groups via its reactive ester moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring fluorinated components for enhanced activity and stability.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the production of specialty polymers, including photosensitive resins and high-performance materials.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) as an electrophilic coupling partner.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacturing of fluorinated electronic materials for display and lighting technologies.
• Peptide Modification: Utilized for selective modification of peptides and proteins, leveraging the reactivity of the maleimide-like pyrrolidinedione group.

Basic Information

Product Name	Methanesulfonic Acid, Trifluoro-, 2-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Ethyl Ester
CAS No.	155863-37-9
Molecular Formula	C7H6F3NO5S
Molecular Weight	273.19 g/mol
Synonyms	2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl trifluoromethanesulfonate; 1-(2-Triflyloxyethyl)pyrrole-2,5-dione; N-(2-Triflyloxyethyl)maleimide; Trifluoromethanesulfonic acid 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl ester; 2-Maleimidoethyl triflate; TfO-CH2CH2-Maleimide; 1-(2-((Trifluoromethyl)sulfonyl)oxy)ethyl)-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our production of Methanesulfonic Acid, Trifluoro-, 2-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. Comprehensive Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.