Description

2H-Pyran-2-One, 3-Acetyl-5,6-Dihydro-4-Hydroxy-6-Methyl-, (R)- (9Ci) is a high-purity, chiral lactone derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and stereochemically defined building block for creating complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and fine chemical industries for applications such as asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for compounds requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a building block in catalytic and stoichiometric asymmetric reactions to introduce the (R)-configured lactone moiety into target molecules.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, and fragrances where its specific structure imparts desired properties.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways involving functionalized lactones.
• Agrochemical Research: Potential intermediate in the development of novel, biologically active compounds for crop protection.

Basic Information

Product Name	2H-Pyran-2-One, 3-Acetyl-5,6-Dihydro-4-Hydroxy-6-Methyl-, (R)- (9Ci)
CAS No.	155553-70-1
Molecular Formula	C8H10O4
Molecular Weight	170.16 g/mol
Synonyms	(R)-3-Acetyl-5,6-dihydro-4-hydroxy-6-methyl-2H-pyran-2-one; (6R)-3-Acetyl-4-hydroxy-6-methyl-5,6-dihydro-2H-pyran-2-one; 3-Acetyl-4-hydroxy-6-methyl-5,6-dihydro-2H-pyran-2-one, (R)-; 4-Hydroxy-6-methyl-3-acetyl-5,6-dihydro-2-pyrone, (R)-; (R)-4-Hydroxy-6-methyl-3-acetyl-5,6-dihydro-2-pyrone; (R)-Dehydroacetic acid lactone derivative; DHA lactone, (R)-isomer
EINECS	Contact for details

Quality Control

Our 2H-Pyran-2-One, 3-Acetyl-5,6-Dihydro-4-Hydroxy-6-Methyl-, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.