Description

Cyclooctanone, 3-Ethynyl- (9Ci) is a specialized organic building block featuring a cyclooctanone core functionalized with a terminal alkyne group. This unique molecular architecture makes it a valuable intermediate for advanced organic synthesis, particularly in the construction of complex macrocycles and functional materials. It is primarily sought by research and development chemists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry, polymer science, and ligand development.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, especially for creating constrained macrocyclic scaffolds via click chemistry or Sonogashira coupling reactions.
• Advanced Material Synthesis: Used in the development of specialty polymers, dendrimers, and molecular machines where the alkyne group enables precise structural modifications and cross-linking.
• Chemical Research & Development: Acts as a versatile building block in academic and industrial R&D for exploring new synthetic methodologies and creating complex organic molecules.
• Ligand and Catalyst Design: Employed in the preparation of novel ligands for catalysis, where the eight-membered ring and alkyne functionality can impart unique steric and electronic properties.
• Agrochemical Intermediate: Potential use in the synthesis of new active ingredients requiring specific, rigid hydrocarbon frameworks.

Basic Information

Product Name	Cyclooctanone, 3-Ethynyl- (9Ci)
CAS No.	155222-55-2
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	3-Ethynylcyclooctanone; 3-Ethynylcyclooctan-1-one; Cyclooctanone, 3-ethynyl-; 155222-55-2; 3-Ethynyl-1-cyclooctanone; 1-Cyclooctanone, 3-ethynyl-
EINECS	Contact for details

Quality Control

Our Cyclooctanone, 3-Ethynyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.