Description

2-Chloro-5-(Tributylstannyl)Pyrimidine is a high-value organotin intermediate, specifically a stannylated pyrimidine derivative, essential for advanced synthetic chemistry. Its core value lies in enabling efficient Stille cross-coupling reactions, a powerful method for forming carbon-carbon bonds in complex molecule construction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in nucleoside and heterocyclic chemistry.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with specific pyrimidine-based structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, via precise molecular coupling.
• Stille Cross-Coupling Reactions: Serves as a pivotal organotin reagent for coupling with aryl, vinyl, or alkynyl halides under palladium catalysis.
• Labeling & Tracer Compounds: Potential use in the synthesis of radiolabeled or isotopically labeled compounds for metabolic and pharmacokinetic studies.
• Ligand & Catalyst Development: Acts as a precursor for creating specialized ligands or organometallic catalysts.

Basic Information

Product Name	2-Chloro-5-(Tributylstannyl)Pyrimidine
CAS No.	155191-68-7
Molecular Formula	C16H29ClN2Sn
Molecular Weight	403.57 g/mol
Synonyms	5-(Tributylstannyl)-2-chloropyrimidine; 2-Chloro-5-(tributylstannyl)pyrimidine; Tributyl(5-chloro-2-pyrimidinyl)stannane; 2-Chloropyrimidin-5-yltributylstannane; Pyrimidine, 2-chloro-5-(tributylstannyl)-; Stannane, tributyl(5-chloro-2-pyrimidinyl)-; 155191-68-7
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Tributylstannyl)Pyrimidine is manufactured and analyzed under strict quality management protocols to ensure consistency and reliability for critical R&D and scale-up processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	<0.5%
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.