Description

4,5-Dichloro-2-(4-Nitrophenyl)Sulfonyl-Pyridazin-3-One is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. Its unique molecular structure, featuring a pyridazinone core with dichloro and sulfonyl substituents, makes it a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Serves as a crucial precursor for developing advanced herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new heterocyclic chemistry, creating libraries of compounds for high-throughput screening.
• Material Science: Potential applications in the development of specialty polymers and functional materials due to its reactive sulfonyl and chloro groups.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	4,5-Dichloro-2-(4-Nitrophenyl)Sulfonyl-Pyridazin-3-One
CAS No.	155164-61-7
Molecular Formula	C10H5Cl2N3O5S
Molecular Weight	366.13 g/mol
Synonyms	4,5-Dichloro-2-[(4-nitrophenyl)sulfonyl]-3(2H)-pyridazinone; 2-(4-Nitrobenzenesulfonyl)-4,5-dichloropyridazin-3(2H)-one; 4,5-Dichloro-2-(4-nitrobenzenesulfonyl)pyridazin-3(2H)-one; 4,5-Dichloro-2-(p-nitrophenylsulfonyl)pyridazin-3-one; Pyridazin-3(2H)-one, 4,5-dichloro-2-[(4-nitrophenyl)sulfonyl]-; 155164-61-7
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-2-(4-Nitrophenyl)Sulfonyl-Pyridazin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications, ensuring traceability and regulatory compliance for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and incompatible materials. For long-term storage, consider using desiccants and an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.