Description

Ethanone, 1-Bicyclo[2.2.2]Oct-5-En-2-Yl-, [1R-(1Alpha,2Beta,4Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral building block used in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures with precise three-dimensional control, which is critical for developing active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce the rigid, functionalized bicyclo[2.2.2]octene scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for use in stereoselective transformations.
• Agrochemical Research: Acts as a building block for creating new, structurally complex active ingredients with potential herbicidal or insecticidal activity.
• Material Science: Utilized in the synthesis of monomers for specialty polymers with unique thermal or mechanical properties derived from the rigid bicyclic core.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new chemical space in discovery programs.

Basic Information

Product Name	Ethanone, 1-Bicyclo[2.2.2]Oct-5-En-2-Yl-, [1R-(1Alpha,2Beta,4Alpha)]- (9Ci)
CAS No.	155156-90-4
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(1R,2S,4R)-1-(Bicyclo[2.2.2]oct-5-en-2-yl)ethan-1-one; (1R,2S,4R)-2-Acetylbicyclo[2.2.2]oct-5-ene; 1-((1R,2S,4R)-Bicyclo[2.2.2]oct-5-en-2-yl)ethanone; [1R-(1α,2β,4α)]-1-Bicyclo[2.2.2]oct-5-en-2-ylethanone; (1R,2S,4R)-1-Bicyclo[2.2.2]oct-5-en-2-ylethanone; Chiral Bicyclo[2.2.2]octenyl Methyl Ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-Bicyclo[2.2.2]Oct-5-En-2-Yl-, [1R-(1Alpha,2Beta,4Alpha)]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to prevent contamination and moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.