Description

3,5-Di-tert-Butylphenyl Trifluoromethanesulfonate is a high-purity, specialty organofluorine compound used as a key intermediate in advanced chemical synthesis. This compound is valued for its role in introducing the trifluoromethanesulfonyl (triflyl) group, a powerful leaving group that facilitates a range of cross-coupling and functionalization reactions. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality building blocks for creating complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the triflate group enables efficient structural elaboration.
• Ligand and Catalyst Preparation: Employed in the manufacture of specialized ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Advanced Material Development: Acts as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: A versatile reagent in Suzuki, Stille, and Negishi couplings due to the high reactivity of the triflate leaving group.
• Organic Synthesis Research: A valuable tool in academic and industrial R&D laboratories for method development and constructing complex molecular architectures.

Basic Information

Product Name	3,5-Di-tert-Butylphenyl Trifluoromethanesulfonate
CAS No.	155064-25-8
Molecular Formula	C15H21F3O3S
Molecular Weight	338.39 g/mol
Synonyms	3,5-Di-tert-butylphenyl triflate; 1,3-Bis(1,1-dimethylethyl)-5-[(trifluoromethyl)sulfonyl]oxy]benzene; 3,5-Bis(tert-butyl)phenyl trifluoromethanesulfonate; 3,5-DTBP Triflate; Trifluoromethanesulfonic acid 3,5-di-tert-butylphenyl ester
EINECS	Contact for details

Quality Control

Our 3,5-Di-tert-Butylphenyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and GC to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.