Description

1-Benzyl 2-(tert-Butyl) Tetrahydro-1,2-Pyridazinedicarboxylate is a high-value, protected heterocyclic building block used in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex nitrogen-containing molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key protected precursor in the synthesis of novel drug candidates, particularly those containing functionalized pyridazine or hydrazine cores.
• Peptidomimetic Research: Serves as a constrained dipeptide isostere or a building block for creating libraries of bioactive compounds that mimic peptide structures.
• Agrochemical Synthesis: Used in the development of new herbicides, insecticides, or fungicides where the pyridazine moiety imparts specific biological activity.
• Ligand and Catalyst Development: Employed as a starting material for synthesizing specialized chelating ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged or modified molecular probes for studying enzyme mechanisms or protein interactions.
• Custom Fine Chemical Production: Supplied for contract manufacturing and custom synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Product Name	1-Benzyl 2-(tert-Butyl) Tetrahydro-1,2-Pyridazinedicarboxylate
CAS No.	154972-38-0
Molecular Formula	C₁₇H₂₄N₂O₄
Molecular Weight	320.38 g/mol
Synonyms	1-Benzyl 2-tert-butyl hexahydropyridazine-1,2-dicarboxylate; 1,2-Dicarboxylic acid, 1,4,5,6-tetrahydropyridazine-, 1-benzyl 2-(1,1-dimethylethyl) ester; tert-Butyl 1-benzyloxycarbonyl-1,4,5,6-tetrahydropyridazine-2-carboxylate; 1-Benzyl 2-(tert-butoxycarbonyl)-1,4,5,6-tetrahydropyridazine; Boc-Pyridazine(OBzl); N-Boc-N'-Cbz-tetrahydropyridazine; 1-Cbz-2-Boc-tetrahydropyridazine; Protected Tetrahydropyridazine Dicarboxylate
EINECS	Contact for details

Quality Control

Our 1-Benzyl 2-(tert-Butyl) Tetrahydro-1,2-Pyridazinedicarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP guidelines for non-clinical development stages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.