Description

Tetrahydro-Pyridazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel pharmaceutical candidates, particularly in medicinal chemistry programs. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Process Chemistry: Serves as a key intermediate in the scale-up and route development for pharmaceutical manufacturing.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and tool compounds for biological target investigation.

Basic Information

Product Name	Tetrahydro-Pyridazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	154972-37-9
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	1-Boc-1,2,3,6-tetrahydropyridazine; tert-Butyl 1,2,3,6-tetrahydro-1-pyridazinecarboxylate; 1,2,3,6-Tetrahydropyridazine-1-carboxylic acid tert-butyl ester; 1-N-Boc-1,2,3,6-tetrahydropyridazine; Boc-1,2,3,6-tetrahydropyridazine; 1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridazine; 1,2,3,6-Tetrahydropyridazine-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Tetrahydro-Pyridazine-1-Carboxylic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.