Description

2(3H)-Furanone,Dihydro-3,4-Dimethyl-5-(1-Methylethyl)-,[3S-(3Alpha,4Bta,5Alpha)]-(9Ci) is a high-purity, stereochemically defined lactone compound with the CAS number 154968-10-2. This specialized chiral intermediate is valued for its precise molecular architecture, which is critical for synthesizing complex molecules with specific biological activity. It is primarily sought after by research institutions and pharmaceutical development teams working on advanced synthetic routes, novel active pharmaceutical ingredients (APIs), and fine chemical production.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly where stereochemical control is paramount.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Fragrance and Flavor Chemistry: Acts as a potential intermediate for creating sophisticated lactone-based aroma compounds due to its substituted furanone structure.
• Agrochemical Research: Employed in the development of new, targeted agrochemicals where specific stereochemistry can influence biological efficacy.
• Material Science Research: Investigated as a monomer or precursor for synthesizing specialized polymers with unique properties.
• Academic and R&D Laboratories: Used in methodological studies and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	2(3H)-Furanone,Dihydro-3,4-Dimethyl-5-(1-Methylethyl)-,[3S-(3Alpha,4Bta,5Alpha)]-(9Ci)
CAS No.	154968-10-2
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	Dihydro-3,4-dimethyl-5-(1-methylethyl)furan-2(3H)-one; (3S,4R,5S)-3,4-Dimethyl-5-(propan-2-yl)dihydrofuran-2(3H)-one; (3S,4R,5S)-3,4-Dimethyl-5-isopropyldihydrofuran-2(3H)-one; 3,4-Dimethyl-5-isopropyl-dihydro-2(3H)-furanone; (3α,4β,5α)-3,4-Dimethyl-5-(1-methylethyl)dihydro-2(3H)-furanone; 154968-10-2; A chiral lactone intermediate
EINECS	Contact for details

Quality Control

Our production of this chiral lactone adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, and NMR to confirm identity, stereochemical purity, and assay. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to moisture and elevated temperatures.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.