Description

Ethanone, 1-[(1R,2S)-2-(Hydroxymethyl)Cyclopropyl]-, Rel- (9Ci) is a specialized chiral building block featuring a cyclopropane ring with hydroxymethyl and ethanone (acetyl) substituents. This compound matters for its role as a key synthetic intermediate in the production of complex, biologically active molecules, where its defined stereochemistry is critical for efficacy. It is primarily needed by pharmaceutical R&D and process chemistry teams for the development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Antiviral Drug Research: Used in the development of antiviral compounds, where the cyclopropane moiety is a common structural motif.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in asymmetric synthesis to induce chirality in target molecules.
• Fine Chemical Production: Utilized in the manufacture of complex fragrances, flavors, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry research and process development in both university and corporate laboratories.

Basic Information

Product Name	Ethanone, 1-[(1R,2S)-2-(Hydroxymethyl)Cyclopropyl]-, Rel- (9Ci)
CAS No.	154615-31-3
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	rel-(1R,2S)-2-(Acetylmethyl)cyclopropanemethanol; 1-[(1R,2S)-2-(Hydroxymethyl)cyclopropyl]ethanone; (1R,2S)-2-(Acetylmethyl)cyclopropanemethanol (rel); Cyclopropanemethanol, 2-(acetylmethyl)-, (1R,2S)-rel-; Chiral Cyclopropyl Acetyl Methanol Derivative; (rel)-(1R,2S)-2-(Hydroxymethyl)cyclopropyl methyl ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1R,2S)-2-(Hydroxymethyl)Cyclopropyl]-, Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity, which is essential for pharmaceutical applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We support compliance with cGMP, ICH Q7 guidelines, and relevant regulatory frameworks to meet the exacting standards of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.