Description

5-Oxo-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-2-Yl Trifluoromethanesulfonate is a high-value, non-racemic triflate ester building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, stereoselective coupling reactions to construct complex molecular architectures. It is primarily sought after by the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its benzoannulen core provides unique biological activity.
• Catalyst & Ligand Development: Serves as a precursor for creating specialized catalysts and chiral ligands used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Cross-Coupling Reactions: An excellent electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the reactivity of the triflate leaving group.
• Academic & R&D: A valuable reagent for methodological development and total synthesis projects in university and industrial research laboratories.

Basic Information

Product Name	5-Oxo-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-2-Yl Trifluoromethanesulfonate
CAS No.	154122-33-5
Molecular Formula	C14H13F3O4S
Molecular Weight	334.31 g/mol
Synonyms	5-Oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl triflate; 2-(Trifluoromethanesulfonyloxy)-5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulene; 5-Oxo-5,6,7,8,9,10-hexahydrobenzo[8]annulen-2-yl trifluoromethanesulfonate; 2-Triflyloxy-5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulene; Benzo[7]annulen-2-ol, 5-oxo-6,7,8,9-tetrahydro-, 2-trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Every batch of 5-Oxo-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-2-Yl Trifluoromethanesulfonate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.