Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Hydroxy-, (1R-Endo)- (9Ci) is a high-purity, chiral bicyclic compound that serves as a critical advanced intermediate in organic synthesis. Its unique stereochemistry and functional groups make it a valuable building block for constructing complex molecular architectures. This product is essential for research and development in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel Active Pharmaceutical Ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce the bicyclo[2.2.1]heptane scaffold, which is a privileged structure in medicinal chemistry.
• Ligand and Catalyst Development: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and Industrial R&D: Used in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Material Science: Potential precursor for advanced polymers or functional materials with specific structural properties.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Hydroxy-, (1R-Endo)- (9Ci)
CAS No.	153923-34-3
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	(1R,2S,4R)-2-Hydroxybicyclo[2.2.1]hept-5-ene-2-carboxylic acid; endo-2-Hydroxybicyclo[2.2.1]hept-5-ene-2-carboxylic acid; (1R-endo)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 2-hydroxy-; 2-Norbornene-2-carboxylic acid, 2-hydroxy-, (1R-endo)-; 153923-34-3; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 2-hydroxy-, (1R,2S,4R)-
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Hydroxy-, (1R-Endo)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure consistent identity, purity, and performance as a critical synthetic intermediate. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Observe all local regulations for the storage of chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.