Description

(R)-(-)-n-Neopentyl-1-Phenyl-2-(1-Piperidino)Ethylamine is a chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its well-defined stereochemistry and structural features, which are critical for creating molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas requiring chiral amine scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, especially those targeting neurological receptors.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize pharmacological profiles.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in R&D laboratories.
• Fine Chemical Synthesis: Acts as a specialized building block for complex natural products and other high-value fine chemicals.

Basic Information

Item	Detail
Product Name	(R)-(-)-n-Neopentyl-1-Phenyl-2-(1-Piperidino)Ethylamine
CAS No.	153837-28-6
Molecular Formula	C18H30N2
Molecular Weight	274.45 g/mol
Synonyms	(R)-(-)-N-Neopentyl-1-phenyl-2-(1-piperidinyl)ethylamine; (R)-N-Neopentyl-1-phenyl-2-piperidin-1-ylethanamine; (R)-1-Phenyl-2-(piperidin-1-yl)-1-(2,2-dimethylpropyl)amine; (R)-N-(2,2-Dimethylpropyl)-1-phenyl-2-(1-piperidinyl)ethylamine; (R)-α-[(2,2-Dimethylpropyl)amino]benzenepropanol, piperidine derivative; (R)-153837-28-6
EINECS	Contact for details

Quality Control

Our (R)-(-)-n-Neopentyl-1-Phenyl-2-(1-Piperidino)Ethylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.