Description

2-Amino-7,7-dimethyl-5-oxo-4-(2-thienyl)-4,6,7,8-tetrahydro-2H-chromene-3-carbonitrile is a versatile and highly functionalized chromene derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its complex molecular architecture, which incorporates amino, cyano, and heterocyclic thienyl groups, making it a valuable precursor for constructing pharmacologically active scaffolds. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in the synthesis of novel heterocyclic compounds for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory agents.
• Organic Synthesis Research: Used in academic and industrial R&D for exploring novel multi-component reactions and constructing complex polycyclic frameworks.
• Material Science Precursor: Investigated for the development of organic semiconductors and non-linear optical (NLO) materials due to its electron-rich chromene core.
• Agrochemical Research: Serves as a starting material for developing new active ingredients with potential herbicidal or insecticidal properties.
• Dye and Pigment Chemistry: The conjugated system can be utilized in the synthesis of specialized dyes and functional colorants.

Basic Information

Item	Details
Product Name	2-Amino-7,7-dimethyl-5-oxo-4-(2-thienyl)-4,6,7,8-tetrahydro-2H-chromene-3-carbonitrile
CAS No.	153790-54-6
Molecular Formula	C₁₆H₁₆N₂O₂S
Molecular Weight	300.38 g/mol
Synonyms	2-Amino-4-(2-thienyl)-7,7-dimethyl-5-oxo-4,6,7,8-tetrahydro-2H-chromene-3-carbonitrile; 4-(2-Thienyl)-2-amino-7,7-dimethyl-5-oxo-4,6,7,8-tetrahydro-2H-chromene-3-carbonitrile; 2-Amino-7,7-dimethyl-5-oxo-4-(thiophen-2-yl)-4,6,7,8-tetrahydro-2H-chromene-3-carbonitrile; Chromene-3-carbonitrile, 2-amino-7,7-dimethyl-5-oxo-4-(2-thienyl)-4,6,7,8-tetrahydro-2H-; Tetrahydrochromene derivative; Knoevenagel condensation product; Thienyl-substituted chromene.
EINECS	Contact for details

Quality Control

Our 2-Amino-7,7-dimethyl-5-oxo-4-(2-thienyl)-4,6,7,8-tetrahydro-2H-chromene-3-carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.