Description

4-Methylphenyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside is a specialized, high-purity thioglycoside derivative used as a critical building block in synthetic organic chemistry. This compound is valued for its role as a glycosyl donor in the stereoselective synthesis of complex oligosaccharides and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic tools, and biochemical probes.

Application

• Glycochemistry Research: Serves as a key intermediate for the synthesis of fucose-containing oligosaccharides and glycans.
• Pharmaceutical Development: Used in the preparation of carbohydrate-based drug candidates, including potential anti-inflammatory and anti-cancer agents.
• Bioconjugation: Acts as a precursor for creating neoglycoconjugates and labeled sugars for biological studies.
• Enzyme Substrate Synthesis: Employed to develop substrates for fucosyltransferase and glycosidase enzyme assays.
• Diagnostic Reagent Manufacturing: Utilized in the production of carbohydrate arrays and detection probes for studying protein-carbohydrate interactions.
• Chemical Biology Tool Development: Integral for creating activity-based probes to study glycosylation processes in cells.

Basic Information

Product Name	4-Methylphenyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside
CAS No.	153658-86-7
Molecular Formula	C19H24O8S
Molecular Weight	412.45 g/mol
Synonyms	p-Tolyl 2,3,4-tri-O-acetyl-1-thio-β-L-fucopyranoside; 1-Thio-β-L-fucopyranoside, 4-methylphenyl 2,3,4-triacetate; 4-Methylphenyl 1-thio-β-L-fucopyranoside 2,3,4-triacetate; p-Tolyl 1-thio-β-L-fucopyranoside triacetate; β-L-Fucopyranoside, 4-methylphenyl 2,3,4-tri-O-acetyl-1-thio-; Thioglycoside donor L-fucose derivative; Acetylated thiofucoside; Fucose thioglycosyl donor.
EINECS	Contact for details

Quality Control

Our production of 4-Methylphenyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized by NMR (1H, 13C), mass spectrometry, and chromatographic methods. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.