Description

3-Chloro-5-Fluorobenzene-1,2-Diamine is a high-purity aromatic diamine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional amine groups and halogen substituents, which enable precise molecular construction for complex target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated benzene core.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing high-performance polymers, such as polyimides and aramids, with enhanced thermal and chemical resistance.
• Dye & Pigment Manufacturing: Serves as a starting material for synthesizing complex organic dyes and pigments, especially azo dyes.
• Ligand & Catalyst Development: Utilized in the preparation of specialized chelating ligands for catalytic systems in asymmetric synthesis.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and organic methodology development.

Basic Information

Item	Details
Product Name	3-Chloro-5-Fluorobenzene-1,2-Diamine
CAS No.	153505-33-0
Molecular Formula	C6H6ClFN2
Molecular Weight	160.58 g/mol
Synonyms	3-Chloro-5-fluoro-1,2-benzenediamine; 3-Chloro-5-fluorobenzene-1,2-diyldiamine; 1,2-Diamino-3-chloro-5-fluorobenzene; 3-Chloro-5-fluoro-o-phenylenediamine; 3-Chloro-5-fluoro-1,2-phenylenediamine; 3-Cl-5-F-C6H2(NH2)2; 153505-33-0 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Fluorobenzene-1,2-Diamine is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.