Description

(S)-(+)-p-Toluenesulfinamide n-Benzylidene is a high-purity chiral sulfinamide derivative, a crucial intermediate in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and ligand for constructing stereogenic centers with high enantioselectivity. This compound is essential for pharmaceutical R&D and fine chemical manufacturers specializing in the production of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• As a chiral auxiliary in the asymmetric synthesis of pharmaceutical intermediates and active ingredients.
• Utilized as a ligand or catalyst component in enantioselective transformations, such as additions to imines.
• Key building block for the research and development of novel therapeutic agents in medicinal chemistry.
• Intermediate in the synthesis of agrochemicals requiring specific stereochemistry for enhanced activity.
• Used in academic and industrial research for developing new methodologies in organic and organometallic chemistry.
• Precursor for the preparation of other chiral sulfinamide derivatives and fine chemicals.

Basic Information

Item	Detail
Product Name	(S)-(+)-p-Toluenesulfinamide n-Benzylidene
CAS No.	153277-49-7
Molecular Formula	C14H13NOS
Molecular Weight	243.32 g/mol
Synonyms	(S)-(+)-N-(Benzylidene)-4-methylbenzenesulfinamide; (S)-N-Benzylidene-p-toluenesulfinamide; (S)-N-Benzylidene-4-methylbenzenesulfinamide; (S)-p-Toluenesulfinamide benzylidene; (S)-(+)-N-(Phenylmethylene)-4-methylbenzenesulfinamide; (S)-4-Methyl-N-(phenylmethylene)benzenesulfinamide; (S)-N-(Benzylidene)-p-toluenesulfinamide
EINECS	Contact for details

Quality Control

Our (S)-(+)-p-Toluenesulfinamide n-Benzylidene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.