Description

5-Iodo-2-Methylpyridazin-3(2H)-One is a halogenated pyridazinone derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its iodine substituent, which serves as an excellent handle for further functionalization via cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of new herbicides, fungicides, and insecticides with potentially improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Cross-Coupling Reactions: The iodine atom makes it an ideal substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex heterocyclic frameworks.

Basic Information

Product Name	5-Iodo-2-Methylpyridazin-3(2H)-One
CAS No.	153239-91-9
Molecular Formula	C5H5IN2O
Molecular Weight	236.01 g/mol
Synonyms	5-Iodo-2-methyl-2H-pyridazin-3-one; 5-Iodo-2-methylpyridazin-3(2H)-one; 2-Methyl-5-iodopyridazin-3(2H)-one; 3(2H)-Pyridazinone, 5-iodo-2-methyl-; 5-Iodo-2-methyl-3(2H)-pyridazinone
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Methylpyridazin-3(2H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.