Description

2,6-Dimethyl-4-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol is a high-value, multifunctional chemical building block featuring a phenolic core substituted with a trifluoromethylated oxadiazole ring. This unique structure provides a combination of steric bulk, electron-withdrawing properties, and potential hydrogen-bonding sites, making it a critical intermediate for advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for developing new drug candidates, particularly in areas targeting CNS disorders, inflammation, and metabolic diseases, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging its structural motifs to improve efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs) due to its phenolic and heterocyclic functionality.
• Polymer & Material Science: Incorporated as a monomer or additive to engineer advanced polymers with specific thermal, optical, or surface properties.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors and light-emitting materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions and synthesizing complex molecular architectures.

Basic Information

Product Name	2,6-Dimethyl-4-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol
CAS No.	153168-59-3
Molecular Formula	C11H9F3N2O2
Molecular Weight	258.20 g/mol
Synonyms	4-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)-2,6-dimethylphenol; 2,6-Dimethyl-4-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)phenol; Phenol, 2,6-dimethyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-; 3-(3,5-Dimethyl-4-hydroxyphenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Every batch of 2,6-Dimethyl-4-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenol is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.