Description

1(2H)-Pyridazineacetic Acid, Tetrahydro--α--Hydroxy-6-Oxo-2-Phenyl- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its complex pyridazine core.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules used in catalysts, ligands, and specialty materials.
• Academic & Industrial R&D: A valuable compound for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of high-value target molecules.

Basic Information

Product Name	1(2H)-Pyridazineacetic Acid, Tetrahydro--α--Hydroxy-6-Oxo-2-Phenyl-
CAS No.	153143-63-6
Molecular Formula	C₁₂H₁₄N₂O₄
Molecular Weight	250.25 g/mol
Synonyms	α-Hydroxy-6-oxo-2-phenyl-1,2,3,6-tetrahydropyridazine-1-acetic acid; 2-Phenyl-1,2,3,6-tetrahydropyridazine-1-acetic acid, α-hydroxy-6-oxo-; Tetrahydro-α-hydroxy-6-oxo-2-phenyl-1(2H)-pyridazineacetic acid; (2R/S)-2-Hydroxy-2-(6-oxo-2-phenyl-1,2,3,6-tetrahydropyridazin-1-yl)acetic acid; 1(2H)-Pyridazineacetic acid, 1,2,3,6-tetrahydro-α-hydroxy-6-oxo-2-phenyl-; 2-Phenyl-1,4,5,6-tetrahydropyridazine-3-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 1(2H)-Pyridazineacetic Acid, Tetrahydro--α--Hydroxy-6-Oxo-2-Phenyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.