Description

S-2-Hydroxyethyl 2,2-Dimethylpropanethioate is a specialized thiocarboxylic acid ester derivative, recognized for its role as a key synthetic intermediate and protecting group in advanced organic synthesis. This compound matters for its ability to introduce thioester functionalities under controlled conditions, enabling the construction of complex molecules with high selectivity. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing sulfur-containing heterocycles and peptide mimetics.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and plant growth regulators requiring specific thioester linkages.
• Polymer Chemistry: Acts as a chain transfer agent (CTA) or functional monomer in the production of specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed as a versatile reagent for introducing the 2,2-dimethylpropanethioate (pivaloylthio) protecting group for alcohols and other functional groups.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing sulfur-containing aroma compounds.
• Material Science Research: Used in surface modification and the creation of self-assembled monolayers (SAMs) on metal surfaces.

Basic Information

Product Name	S-2-Hydroxyethyl 2,2-Dimethylpropanethioate
CAS No.	153121-88-1
Molecular Formula	C7H14O2S
Molecular Weight	162.25 g/mol
Synonyms	2-Hydroxyethyl Pivaloyl Sulfide; 2-Hydroxyethyl Pivalate Sulfide; 2-Hydroxyethyl 2,2-Dimethylpropane-1-thioate; 2,2-Dimethylpropanoic Acid S-(2-Hydroxyethyl) Ester; Pivalic Acid S-2-Hydroxyethyl Ester; S-(2-Hydroxyethyl) Pivalothioate; 1-Thia-4-oxa-2,2-dimethylpentan-5-one
EINECS	Contact for details

Quality Control

Our S-2-Hydroxyethyl 2,2-Dimethylpropanethioate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its easily oxidized nature, minimize headspace in opened containers and handle under inert gas when possible to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.