Description

1-Propanesulfonamide, 2,2-Dimethyl-3-((1,2,4)Triazolo(1,5-B)Pyridazin- 6-Yloxy)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides or fungicides, where the triazolopyridazine moiety can contribute to specific biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic systems for material science or catalyst ligand development.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production runs under current Good Manufacturing Practice (cGMP) guidelines where applicable.

Basic Information

Product Name	1-Propanesulfonamide, 2,2-Dimethyl-3-((1,2,4)Triazolo(1,5-B)Pyridazin- 6-Yloxy)-
CAS No.	152537-14-9
Molecular Formula	C11H15N5O3S
Molecular Weight	297.33 g/mol
Synonyms	2,2-Dimethyl-3-(([1,2,4]triazolo[1,5-b]pyridazin-6-yl)oxy)propane-1-sulfonamide; 3-((1,2,4-Triazolo[1,5-b]pyridazin-6-yl)oxy)-2,2-dimethyl-1-propanesulfonamide; 152537-14-9; 6-((3-Sulfamoyl-2,2-dimethylpropoxy)-[1,2,4]triazolo[1,5-b]pyridazine
EINECS	Contact for details

Quality Control

Our production of 1-Propanesulfonamide, 2,2-Dimethyl-3-((1,2,4)Triazolo(1,5-B)Pyridazin- 6-Yloxy)- adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We support compliance with relevant regulatory frameworks, including REACH, and can provide material for projects requiring ICH guideline stability studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.