Description

1-(4-Chlorophenyl)-4,4-Dimethyl-2-(4H-1,2,4-Triazol-4-Yl)Pentan-3-Ol is a high-purity, non-racemic chiral building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a chlorophenyl group, a dimethyl-substituted carbon chain, and a 1,2,4-triazole moiety, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its defined stereochemistry and high purity are critical for ensuring the efficacy and specificity of the final target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation fungicides and pesticides, where the triazole ring is a common bioactive component.
• Chemical Research: Acts as a valuable standard or starting material in academic and industrial laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Ligand Precursor: Potential use in the synthesis of specialized ligands for catalysis or metal-organic frameworks (MOFs) due to the presence of nitrogen donor atoms.

Basic Information

Item	Details
Product Name	1-(4-Chlorophenyl)-4,4-Dimethyl-2-(4H-1,2,4-Triazol-4-Yl)Pentan-3-Ol
CAS No.	152450-21-0
Molecular Formula	C15H20ClN3O
Molecular Weight	293.79 g/mol
Synonyms	(2R,3S)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol; (2R,3S)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(4H-1,2,4-triazol-4-yl)pentan-3-ol; UNII-9FZ6S7B91K; 9FZ6S7B91K; Pentan-3-ol, 1-(4-chlorophenyl)-4,4-dimethyl-2-(4H-1,2,4-triazol-4-yl)-, (2R,3S)-; (2R,3S)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pentan-3-ol; (2R,3S)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-3-pentanol
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-4,4-Dimethyl-2-(4H-1,2,4-Triazol-4-Yl)Pentan-3-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.