Description

(2-Naphthyl)Methylzinc Bromide is a specialized organozinc reagent, a key building block in modern synthetic organic chemistry. Its value lies in enabling efficient carbon-carbon bond formation, particularly in Negishi cross-coupling reactions, which are critical for constructing complex molecular architectures. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and selective synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for introducing the 2-naphthylmethyl moiety into active pharmaceutical ingredients (APIs) and drug candidates.
• Negishi Cross-Coupling Reactions: Used as a nucleophilic coupling partner with aryl, heteroaryl, and vinyl halides/pseudohalides to form new C-C bonds with high selectivity.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides that incorporate naphthalene-based structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science & OLED Development: Used in the synthesis of organic semiconductors, charge-transport materials, and luminescent compounds for electronic devices.
• Fine Chemical and Flavor/Fragrance Synthesis: Facilitates the construction of complex, polycyclic aromatic structures found in high-value specialty chemicals.

Basic Information

Product Name	(2-Naphthyl)Methylzinc Bromide
CAS No.	152329-44-7
Molecular Formula	C11H11BrZn
Molecular Weight	272.50 g/mol
Synonyms	2-Naphthylmethylzinc Bromide; (2-Naphthalenylmethyl)zinc Bromide; Bromo(2-naphthylmethyl)zinc; Zinc, bromo(2-naphthalenylmethyl)-; (2-Naphthylmethyl)zinc Bromide Solution; (2-Naphthyl)Methyl Zinc Bromide
EINECS	Contact for details

Quality Control

Every batch of (2-Naphthyl)Methylzinc Bromide is manufactured and handled under strict inert atmosphere conditions to ensure stability and reactivity. Our quality assurance includes rigorous analytical testing to confirm identity, purity, and concentration. A comprehensive Certificate of Analysis (COA) detailing assay (by titration or ICP), solvent content, and impurity profile is provided with each shipment to guarantee it meets your research and process development specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions or as specified. Keep the container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zn basis)	≥ 95%
Solvent (THF)	Balance
Water Content (KF)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.