Description

3-Sulfosuccinimid-1-Yl Acetate is a high-purity, reactive chemical intermediate primarily used in bioconjugation and protein modification processes. Its core value lies in its ability to introduce functional groups for crosslinking, enabling the development of advanced diagnostic reagents and therapeutic conjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality building blocks for their synthesis workflows.

Application

• Bioconjugation Reagent: A key intermediate for synthesizing amine-reactive crosslinkers like sulfo-NHS acetate derivatives.
• Protein Labeling & Modification: Used to introduce acetyl or other functional groups onto proteins, antibodies, and peptides for analytical or therapeutic purposes.
• Diagnostic Assay Development: Serves in the production of enzyme conjugates and labeled probes for immunoassays (ELISA, lateral flow) and histochemistry.
• ADC (Antibody-Drug Conjugate) Research: A valuable building block in the linker chemistry for constructing next-generation targeted cancer therapies.
• Biomaterial & Surface Functionalization: Enables the modification of polymers, nanoparticles, and sensor surfaces with bioactive molecules.
• Chemical Biology Tool: Facilitates the study of protein function and interaction through site-specific tagging and pull-down assays.

Basic Information

Product Name	3-Sulfosuccinimid-1-Yl Acetate
CAS No.	152305-87-8
Molecular Formula	C6H6NO7S
Molecular Weight	236.18 g/mol
Synonyms	1-(Carboxymethyl)-3-sulfosuccinimide; 3-Sulfosuccinimidyl Acetate; N-(Carboxymethyl)-3-sulfosuccinimide; Sulfo-NHS Acetate; 1-Acetoxy-3-sulfosuccinimide; N-Hydroxysulfosuccinimide Acetate; 3-Sulfo-N-hydroxysuccinimidyl Acetate; Acetic Acid 3-Sulfo-N-succinimidyl Ester
EINECS	Contact for details

Quality Control

Our 3-Sulfosuccinimid-1-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMF, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.